POLA DISTRIBUSI BRONKIEKTASIS DI POLIKLINIK PARU RSU DR. SOEDARSO PONTIANAK PERIODE JANUARI – DESEMBER Epilepsi Tipe Grand-Mal Dengan Bukan Penderita Epilepsi. Jurnal .. Alsagaff H, Mukty A. Bronkiektasis, Dasar-dasar Ilmu Penyakit Paru. 20 Bronkitis akut. 4A. 21 Bronkiolitis akut. 3B. 22 Bronkiektasis. 3A. 23 Displasia bronkopulmonar. 1. 24 Karsinoma paru. 2. 25 Pneumonia, bronkopneumonia.
|Published (Last):||16 January 2013|
|PDF File Size:||1.4 Mb|
|ePub File Size:||15.86 Mb|
|Price:||Free* [*Free Regsitration Required]|
Skip broniiektasis main content. Log In Sign Up. A series of novel derivatives of Tetrahydrobenzothienopyrimidine hydrazone were synthesized and product structure was elucidated by 1NMR, C13NMR and mass spectroscopy. The synthesized compounds were evaluated against fungal and bacterial The synthesized compounds were evaluated against fungal and bacterial strains.
Some derivatives showed promising result against gram positive, gram negative bacterial and fungal strains than standard drug ampicillin and grieseofulvin.
In99, an Inrelated integron, its occurrence and prevalence in clinical Pseudomonas aeruginosa strains from a central region of Portugal. Bronchiectasis is characterized by irreversible widening of the medium-sized airways ectasiawith inflammation, chronic bacterial infection and destruction of the bronchial walls.
This could be due to genetic constitusional state or This could be due to genetic constitusional state or episodic insidental state which not related to intrinsic imunity. The pathogenesis of bronchiectasis is a combination of repeated inflammation and parenchymal fibrotic, lead to bronchial wall weakening and bronchial irreversibly dilatation.
The diagnosis of bronchiectasis is made on the basis of high-resolution computed tomography HRCT scan findings. Additional testmay be required in spesific clinical setting. Treatment strategies including antibiotic therapy in btonkiektasis exacerbation and in controlling the microbial growth, therapy according to intrinsic conditional state, therapy to controll the excessive inflammation, promote bronchial hygiene, and consideration of surgery in some cases.
In bgonkiektasis review, we will describethe etiologies, pathogenesis, diagnostic investigation, and treatment strategies. Manifestasi klinis primer bronkiektasis adalah terjadinya infeksi yang berulang, kronis, atau refrakter, dengan gejala sisa yang terjadi adalah batuk darah, obstruksi saluran napas kronis, dan gangguan bernapas secara progresif.
Penurunan angka FEV 1, skor gejala sesak lanjut, hasil kultur positif Pseudomonas, indeks metabolisme basal yang rendah, laki-laki, usia lanjut, dan PPOK telah diidentifikasi sebagai faktor risiko untuk mortalitas.
Klasifikasi Secara morfologis bronkiektasis dibagi 3 tipe dapat dilihat pada gambar 1: Model ini menjelaskan individu yang memiliki predisposisi terjadi respons inflamasi hebat terhadap infeksi paru atau jejas terhadap jaringan.
Inflamasi yang terjadi sebagian bertanggungjawab terhadap kerusakan struktural saluran napas. Abnormalitas struktural yang terjadi menyebabkan. Determinants of the microbiological water quality of indoor swimming-pools in relation to disinfection. Phytochemical investigation of the bark of Guatteria hispida bronkiekttasis three new alkaloids, 9-methoxy-O-methylmoschatoline 19-methoxyisomoschatoline 2and isocerasonine 3along with 10 known alkaloids, 8-oxopseudopalmatine 4Phytochemical investigation of the bark of Guatteria hispida afforded three new alkaloids, 9-methoxy-O-methylmoschatoline 19-methoxyisomoschatoline 2and isocerasonine 3along with 10 known alkaloids, 8-oxopseudopalmatine 4O-methylmoschatoline 5lysicamine 6liriodenine 7methoxyliriodenine 8nornuciferine 9anonaine 10xylopine 11coreximine 12and isocoreximine Compounds 5, 6, and 7 were active against S.
Significantly enhanced antibacterial activity of Ag-doped TiO 2 nanofibers synthesized by electrospinning. Survey of childhood empyema in Asia: Implications for detecting the unmeasured burden of culture-negative bacterial disease. Investigation of enhancement of solubility of norfloxacin beta-cyclodextrin in presence of acidic solubilizing additives.
The present study is aimed at improving the solubility of a poorly water-soluble drug, norfloxacin by incorporating solubilizing additives such as ascorbic acid and citric acid into the beta-cyclodextrin complexes.
Junral, being amphoteric in nature, exhibits a higher solubility at pH bronkiektsais 4 and above 8. Addition of substances like ascorbic acid and citric acid in beta-cyclodextrin complexes reduces the pH of the immediate microenvironment of the drug below pH 4. In the present work, beta-cyclodextrin complexes of norfloxacin were prepared along with solubilizing additives such as citric acid and ascorbic acid in various proportion and the dissolution profile was performed in both HCl buffer, pH 1.
The results have shown an enhanced dissolution rate in both media.
DSC and IR spectral studies performed on the solid complexes have shown that there is no interaction of the drug with the additives and beta-cyclodextrin. Disc bronkiektassi studies have sh The antimicrobial activity of doripenem in comparison of imipenem, meropenem and ertapenem among Pseudomonas aeruginosa isolated from burn and Cystic Fibrosis CF patients were determined.
The in vitro susceptibilities of doripenem, imipenem, meropenem and ertapenem were determined by Etests.
Jurnal Respirologi Indonesia
Among isolates which were resistant to imipenem, 16 isolates were positive for the bla IMP gene. All isolates had no bla VIM gene. All MBL producing isolates were excluded. The susceptibility rate of doripenem is higher than that of imipenem and meropenem among P.
The emergence of multi-drug resistant microorganisms presents a critical problem for patients undergoing surgery. Acidic pH, which is produced by oxidized regenerated cellulose ORCis a broad-spectrum physiological detriment to Acidic pH, which is produced by oxidized regenerated cellulose ORCis a broad-spectrum physiological detriment to survival of microorganisms known to cause surgical infections. The purpose of this study was to examine the antimicrobial effect of ORC against antibiotic-resistant organisms.
Plate counts were performed at 0, 1, 6, and 24 h. Antimicrobial activity was seen with all three ORC products against the challenge organisms. Data indicate that antibiotic-resistant microorganisms remain susceptible to the antimicrobial activity of ORC.
Since low pH affects a relatively broad-spectrum of bacteria and does not act in a mechanism-specific manner, as do antibiotics, antibiotic-resistant strains of bacteria are unlikely to resist the ORC pH effect. Results of this in vitro assessment support the hypothesis that the antimicrobial activity of ORC is effective against antibiotic-resistant microorganisms.
Desferrioxamine and desferrioxamine-caffeine as carriers of aluminum and gallium to microbes via the Trojan Horse Effect. Iron acquisition by bacteria and fungi involves in several cases the promiscuous usage of siderophores. Thus, antibiotic resistance from these microorganisms can be circumvented through a strategy of loading toxic metals into siderophores Thus, antibiotic resistance from these microorganisms can be circumvented through a strategy of loading toxic metals into siderophores Trojan Horse Effect.
Desferrioxamine dfo and its cell-permeant derivative desferrioxamine-caffeine dfcaf were complexed with aluminum or gallium for this purpose.
Their relative stabilities were studied through competitive equilibria with fluorescent probes calcein, fluorescein-desferrioxamine and 8-hydroxyquinoline.
Wide spectrum antimicrobial action can be obtained by loading non-essential or toxic metal ions to microbes via a convenient siderophore carrier.
Salicylate inhibition of Acanthamoeba attachment to contact lenses: Acanthamoeba attachment adsorption to hydrogel contact lenses is enhanced by Pseudomonas aeruginosa biofilm.
The effect of sodium salicylate on Acanthamoeba attachment to biofilm-coated and uncoated hydrogel lenses was investigated The effect of sodium salicylate on Acanthamoeba attachment to biofilm-coated and uncoated hydrogel lenses jrunal investigated. A minimum of 16 replicates were used for each test condition; a control condition using clean lenses without biofilm was included.
Four groups of hydrogel contact lenses etafilcon A were pretreated with P. In addition, two more groups remained untreated. Quartered lenses of all six groups were bronkiekfasis incubated in a suspension of A.
Two batches of lenses had either 3 or 30 mM sodium salicylate added to the bacterial suspension stage 1 intervention. Two other batches of lenses had salicylate added to the amoebal suspension stage 2 intervention. One of the batches, which had a stage 1 intervention, had salicylate added at the second stage as well. The remaining batches receive Microbial keratitis in Hong Kong: Enhanced attachment of bronkiektassis to extended-wear silicone hydrogel contact lenses.
To establish if silicone hydrogel S-H contact lenses could be a risk factor for Acanthamoeba infection by facilitating the attachment of trophozoites to their surface and transfer to the cornea and to determine the effect Acanthamoeba To establish if silicone hydrogel S-H contact lenses could be a risk factor for Acanthamoeba infection by facilitating the attachment of trophozoites to their surface and transfer brlnkiektasis the cornea and to determine the bronkiektasls Acanthamoeba culture technique, patient wear, and Pseudomonas biofilm coating have on attachment to the S-H lens.
Attachment to a S-H lens was compared with that of a conventional hydrogel control lens. Sixteen replicates were carried out for both brpnkiektasis types under each test condition.
Unworn, worn, and Pseudomonas biofilm coated S-H and hydrogel quarters were incubated for 90 minutes with plate-cultured trophozoites. Juurnal attached to one surface of each lens quarter were counted by direct light microscopy. Logarithmic transformation of data allowed the use of a parametric analysis of variance. Acanthamoebal attachment to the S-H lenses was significantly greater than to the conventional hydrogel.
Liquid-cultured trophozoites demonstrated a higher affinity bronkiektassis the lenses tested.
Wear and bacterial biofilm coating had no effect on attachment to S-H lenses. The bronkiektasie attachment found with the S-H lens may be an inherent characteristic of the polymer or a side effect of the surface treatment procedure to which the lenses are exposed.
It is possible that S-H lenses are at greater risk of promoting Acanthamoeba infection if exposed to the organism because of the enhanced attachment characteristic of this new material. Epidemiology of Pseudomonas aeruginosa keratitis in contact lens wearers. Prosthesis culture 6 months after implantation and the effect of haematogenous seeding in a rat model. The aim of this study was to investigate the role of haematogenous seeding in late prosthesis infection. In all, 45 male Wistar albino rats were divided into three equal groups.
A small piece of silicone prosthesis was implanted into the A small piece of silicone prosthesis was implanted into the scrotum of all rats under sterile condition and antibiotic prophylaxis.
In the first group, all silicones were removed after 6 months without any complication and were cultured for bacterial growth. In the second group, a disc, which was saturated with Staphylococcus epidermidis, was inoculated subcutaneously in the legs of the rats in the 6th month, revealing a nodule formation days after the inoculation and treated with an appropriate antibiotic after the nodule formation.
In the third group, the same disc was inoculated, but all rats were treated immediately from the inoculation time onwards. The silicones of the second and third group were also removed at the end of the 6th month and were cultured to observe the bacterial growth.
Clinical impact and risk factors for percutaneous gastrostomy wound infections due to resistant organisms. Synthesis and antibacterial activity of substituted flavones, 4-thioflavones and 4-iminoflavones. Synthesis of flavones, 4-thioflavones and 4-iminoflavones was carried out with the substitution of variable halogens, methyl, methoxy and nitro groups in the A, B and AB rings of the respective compounds and we also report here their Synthesis of flavones, 4-thioflavones and 4-iminoflavones was carried out with the substitution of variable halogens, methyl, methoxy and nitro groups in the A, B and AB rings of the respective compounds and we also report here their antibacterial activity.
Most of the synthesized